We study viruses that pose a threat to The Health Of billions
of people around the globe.
Hepatitis C virus, Dengue, and Zika viruses are positive-sense RNA viruses of the Flaviviridae family. Our lab uses state-of-the art molecular biology, biochemistry and high-throughput approaches to investigate RNA-RNA and protein-RNA interactions important for regulation of viral gene expression, replication, immune evasion, and pathogenesis. Our research will aid in improving our understanding of how these positive-sense RNA viruses usurp the host cell, replicate their genomes, and cause disease. We hope to gain insight into RNA regulation and identify novel avenues for antiviral intervention.
Congratulations to Jasmin Chahal on her 3rd prize for Best Oral Presentation (Ph.D. Candidate Category) at the Annual Microbiology & Immunology Graduate Student Research Day!
In addition to her Primary Appointment in the Department of Microbiology & Immunology, Dr. Selena Sagan is now an Associate Member of the Department of Biochemistry at McGill University
A new mouse model with a working immune system could be used in laboratory research to improve understanding of Zika virus infection and aid development of new treatments, according to a study published in PLOS Pathogens.