Congratulations to Rachel Hayes and Carolina Camargo, as well as our collaborators Ahmed Oraby and David Marchant (University of Alberta) who recently published a manuscript from Rachel’s M.Sc. research on Respiratory Syncytial Virus (RSV). Rachel performed alanine-scanning mutagenesis on the RSV receptor, IGF1R, and identified a mutation that significantly reduced RSV infection. Further analysis revealed that this mutation disrupted a hydrogen bonding network that may be important for both IGF1R maturation and RSV infection. Check it out here:
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001951#tab2